Columbus Crew vs LA Galaxy: Home team to win
New York City vs FC Cincinnati: Home team to win
NY Red Bulls vs DC United: Home team to win
Orlando City vs Charlotte FC: Home or away win
Toronto vs Philadelphia Un: Home team to win
Atlanta Utd vs New England Rev: Home win or draw
Dallas vs Minnesota Utd: Draw
Houston Dynamo vs San Diego FC: Home team to win
Real Salt Lake vs Inter Miami: Home or away win
Los Angeles FC vs Colorado Rapids: Home team to win
SJ Earthquakes vs Austin FC: Home team to win
| H | C | L | Teams | 1% | X% | 2% | T |
|---|---|---|---|---|---|---|---|
| 00:30 | Usa1 | USA – MLS | Columbus Crew vs LA Galaxy | 40 | 32 | 28 | 1 |
| 00:30 | Usa1 | USA – MLS | New York City vs FC Cincinnati | 40 | 31 | 29 | 1 |
| 00:30 | Usa1 | USA – MLS | NY Red Bulls vs DC United | 50 | 23 | 27 | 1 |
| 00:30 | Usa1 | USA – MLS | Orlando City vs Charlotte FC | 35 | 30 | 35 | 12 |
| 00:30 | Usa1 | USA – MLS | Toronto vs Philadelphia Un | 51 | 29 | 20 | 1 |
| 00:45 | Usa1 | USA – MLS | Atlanta Utd vs New England Rev | 38 | 32 | 30 | 1X |
| 01:30 | Usa1 | USA – MLS | Dallas vs Minnesota Utd | 38 | 31 | 31 | X |
| 01:30 | Usa1 | USA – MLS | Houston Dynamo vs San Diego FC | 39 | 30 | 31 | 1 |
| 02:30 | Usa1 | USA – MLS | Real Salt Lake vs Inter Miami | 37 | 30 | 33 | 12 |
| 03:30 | Usa1 | USA – MLS | Los Angeles FC vs Colorado Rapids | 44 | 31 | 25 | 1 |
| 03:30 | Usa1 | USA – MLS | SJ Earthquakes vs Austin FC | 50 | 26 | 24 | 1 |
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